Entity Details

Primary name MTA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BTC8
EntryNameMTA3_HUMAN
FullNameMetastasis-associated protein MTA3
TaxID9606
Evidenceevidence at protein level
Length594
SequenceStatuscomplete
DateCreated2003-02-28
DateModified2021-06-02

Ontological Relatives

GenesMTA3

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0016575 histone deacetylation
GO:0016581 NuRD complex
GO:0042826 histone deacetylase binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0044877 protein-containing complex binding
GO:0045892 negative regulation of transcription, DNA-templated

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000679 Zinc finger, GATA-typeDomainDomain
IPR000949 ELM2 domainDomainDomain
IPR001005 SANT/Myb domainDomainDomain
IPR001025 Bromo adjacent homology (BAH) domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017884 SANT domainDomainDomain
IPR035170 Metastasis-associated protein MTA1, R1 domainDomainDomain
IPR040138 Mesoderm induction early response protein/metastasis-associated proteinFamilyFamily
IPR043151 Bromo adjacent homology (BAH) domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
MTA3_HUMANKDM1A_HUMANBioGRID, IntAct19703393 21937684 26028330 details
MTA3_HUMANARNT_HUMANBioGRID, IntAct21988832 details
MTA3_HUMANAKT1_HUMANBioGRID, MINT25640309 details
MTA3_HUMANATM_HUMANBioGRID, MINT25640309 details
MTA3_HUMANAURKA_HUMANBioGRID, MINT25640309 details
MTA3_HUMANBAG4_HUMANBioGRID, MINT25640309 details
MTA3_HUMANBCAR3_HUMANBioGRID, MINT25640309 details
MTA3_HUMANCADH1_HUMANMINT25640309 details
MTA3_HUMANCDN2C_HUMANBioGRID, MINT25640309 details
MTA3_HUMANFGFR2_HUMANBioGRID, MINT25640309 details
MTA3_HUMANFGFR4_HUMANBioGRID, MINT25640309 details
MTA3_HUMANIGF1R_HUMANBioGRID, MINT25640309 details
MTA3_HUMANNOTC2_HUMANBioGRID, MINT25640309 details
MTA3_HUMANPARP1_HUMANBioGRID, MINT25640309 details
MTA3_HUMANTGFB1_HUMANBioGRID, MINT25640309 details
MTA3_HUMANTS101_HUMANBioGRID, MINT25640309 details
MTA3_HUMANGATA3_HUMANIntAct26028330 details
MTA3_HUMANEHMT2_HUMANIntAct26028330 details
MTA3_HUMANBCL6_HUMANBioGRID15454082 17545502 details
MTA3_HUMANNACC2_HUMANBioGRID22926524 details
MTA3_HUMANFZR1_HUMANBioGRID25640309 details
MTA3_HUMANFOXK2_HUMANBioGRID27773593 details
MTA3_HUMANUBP43_HUMANBioGRID30135474 details
MTA3_HUMANERPG3_HUMANBioGRID31722399 details
MTA3_HUMANERCC6_HUMANBioGRID31722399 details
MTA3_HUMANHDAC1_HUMANBioGRID, IntAct, MINT12705869 18451879 21258344 22075476 23752268 24981860 26028330 26344197 26496610 28514442 details
MTA3_HUMANHDAC2_HUMANBioGRID, IntAct, MINT12705869 18451879 21258344 23752268 24981860 26028330 26344197 26949739 30737378 details
MTA3_HUMANCHD4_HUMANBioGRID, IntAct21258344 22075476 24981860 26028330 26344197 28977666 details
MTA3_HUMANMBD3_HUMANBioGRID, IntAct, MINT12705869 21258344 24981860 25123934 26028330 26344197 details
MTA3_HUMANCDKA1_HUMANBioGRID, MINT21258344 24981860 25123934 26496610 details
MTA3_HUMANCHD3_HUMANBioGRID, IntAct12705869 24981860 26344197 28977666 details
MTA3_HUMANFOG2_HUMANBioGRID18067919 details
MTA3_HUMANJUN_HUMANBioGRID21196933 details
MTA3_HUMANSMRCD_HUMANBioGRID21549307 details
MTA3_HUMANRAD21_HUMANBioGRID22075476 details
MTA3_HUMANKDM5B_HUMANBioGRID21937684 details
MTA3_HUMANHM20B_HUMANBioGRID21258344 details
MTA3_HUMANHM20A_HUMANBioGRID21258344 details
MTA3_HUMANGSE1_HUMANBioGRID21258344 details
MTA3_HUMANRCOR3_HUMANBioGRID21258344 details
MTA3_HUMANRCOR1_HUMANBioGRID21258344 details
MTA3_HUMANCHD5_HUMANBioGRID24981860 25247294 details
MTA3_HUMANPHF1_HUMANBioGRID24981860 29846670 details
MTA3_HUMANGRB2_HUMANHPRD11483358 details