Entity Details

Primary name LOXE3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BYJ1
EntryNameLOXE3_HUMAN
FullNameHydroperoxide isomerase ALOXE3
TaxID9606
Evidenceevidence at protein level
Length711
SequenceStatuscomplete
DateCreated2003-01-27
DateModified2021-06-02

Ontological Relatives

GenesALOXE3

GO terms

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GOName
GO:0005506 iron ion binding
GO:0005829 cytosol
GO:0006665 sphingolipid metabolic process
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0019233 sensory perception of pain
GO:0019369 arachidonic acid metabolic process
GO:0019372 lipoxygenase pathway
GO:0035357 peroxisome proliferator activated receptor signaling pathway
GO:0043651 linoleic acid metabolic process
GO:0045444 fat cell differentiation
GO:0046513 ceramide biosynthetic process
GO:0050486 intramolecular transferase activity, transferring hydroxy groups
GO:0051120 hepoxilin A3 synthase activity
GO:0051122 hepoxilin biosynthetic process
GO:0061436 establishment of skin barrier
GO:0106255 hydroperoxy icosatetraenoate isomerase activity
GO:0106256 hydroperoxy icosatetraenoate dehydratase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000907 LipoxygenaseFamilyFamily
IPR001024 PLAT/LH2 domainDomainDomain
IPR001885 Lipoxygenase, mammalianFamilyFamily
IPR013819 Lipoxygenase, C-terminalDomainDomain
IPR020833 Lipoxygenase, iron binding siteSiteBinding site
IPR020834 Lipoxygenase, conserved siteSiteConserved site
IPR036226 Lipoxigenase, C-terminal domain superfamilyFamilyHomologous superfamily
IPR036392 PLAT/LH2 domain superfamilyFamilyHomologous superfamily
IPR042062 Lipoxygenase, vertebrates, PLAT domainDomainDomain

Diseases

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Interactions

4 interactions