Entity Details

Primary name TPK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H3S4
EntryNameTPK1_HUMAN
FullNameThiamin pyrophosphokinase 1
TaxID9606
Evidenceevidence at protein level
Length243
SequenceStatuscomplete
DateCreated2004-03-01
DateModified2021-06-02

Ontological Relatives

GenesTPK1

GO terms

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GOName
GO:0004788 thiamine diphosphokinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006772 thiamine metabolic process
GO:0009229 thiamine diphosphate biosynthetic process
GO:0016301 kinase activity
GO:0030975 thiamine binding
GO:0042723 thiamine-containing compound metabolic process
GO:0042802 identical protein binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR006282 Thiamin pyrophosphokinaseFamilyFamily
IPR007371 Thiamin pyrophosphokinase, catalytic domainDomainDomain
IPR007373 Thiamin pyrophosphokinase, thiamin-binding domainDomainDomain
IPR016966 Thiamin pyrophosphokinase, eukaryoticFamilyFamily
IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamilyFamilyHomologous superfamily
IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00152 ThiamineDrugbanksmall molecule
DB04768 Pyrithiamine PyrophosphateDrugbanksmall molecule

Interactions

3 interactions