Entity Details

Primary name PIF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H611
EntryNamePIF1_HUMAN
FullNameATP-dependent DNA helicase PIF1
TaxID9606
Evidenceevidence at protein level
Length641
SequenceStatuscomplete
DateCreated2005-07-19
DateModified2021-06-02

Ontological Relatives

GenesPIF1

GO terms

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GOName
GO:0000002 mitochondrial genome maintenance
GO:0000287 magnesium ion binding
GO:0000781 chromosome, telomeric region
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005739 mitochondrion
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0007004 telomere maintenance via telomerase
GO:0010521 telomerase inhibitor activity
GO:0017116 single-stranded DNA helicase activity
GO:0032204 regulation of telomere maintenance
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032508 DNA duplex unwinding
GO:0033678 5'-3' DNA/RNA helicase activity
GO:0042162 telomeric DNA binding
GO:0043139 5'-3' DNA helicase activity
GO:0051880 G-quadruplex DNA binding
GO:0051974 negative regulation of telomerase activity

Subcellular Location

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Subcellular Location
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR003840 DNA helicaseFamilyFamily
IPR010285 DNA helicase Pif1-likeFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PIF1_HUMANHSF2_HUMANIntAct25036637 details