Entity Details

Primary name CP4FC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HCS2
EntryNameCP4FC_HUMAN
FullNameCytochrome P450 4F12
TaxID9606
Evidenceevidence at protein level
Length524
SequenceStatuscomplete
DateCreated2002-05-10
DateModified2021-06-02

Ontological Relatives

GenesCYP4F12

GO terms

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GOName
GO:0000038 very long-chain fatty acid metabolic process
GO:0001676 long-chain fatty acid metabolic process
GO:0003091 renal water homeostasis
GO:0003095 pressure natriuresis
GO:0005506 iron ion binding
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0006631 fatty acid metabolic process
GO:0008391 arachidonic acid monooxygenase activity
GO:0008392 arachidonic acid epoxygenase activity
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0017144 drug metabolic process
GO:0018685 alkane 1-monooxygenase activity
GO:0019369 arachidonic acid metabolic process
GO:0019373 epoxygenase P450 pathway
GO:0020037 heme binding
GO:0036101 leukotriene B4 catabolic process
GO:0042360 vitamin E metabolic process
GO:0042361 menaquinone catabolic process
GO:0042376 phylloquinone catabolic process
GO:0042377 vitamin K catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0050051 leukotriene-B4 20-monooxygenase activity
GO:0055078 sodium ion homeostasis
GO:0070330 aromatase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002401 Cytochrome P450, E-class, group IFamilyFamily
IPR017972 Cytochrome P450, conserved siteSiteConserved site
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01026 KetoconazoleDrugbanksmall molecule

Interactions

5 interactions