Entity Details

Primary name ASH1L_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR48
EntryNameASH1L_HUMAN
FullNameHistone-lysine N-methyltransferase ASH1L
TaxID9606
Evidenceevidence at protein level
Length2969
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesASH1L

GO terms

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GOName
GO:0001501 skeletal system development
GO:0002674 negative regulation of acute inflammatory response
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005794 Golgi apparatus
GO:0005923 bicellular tight junction
GO:0007338 single fertilization
GO:0009791 post-embryonic development
GO:0030317 flagellated sperm motility
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043409 negative regulation of MAPK cascade
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046697 decidualization
GO:0046872 metal ion binding
GO:0046974 histone methyltransferase activity (H3-K9 specific)
GO:0046975 histone methyltransferase activity (H3-K36 specific)
GO:0061038 uterus morphogenesis
GO:0097676 histone H3-K36 dimethylation
GO:1903699 tarsal gland development
GO:1903709 uterine gland development

Subcellular Location

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Subcellular Location
Cell junction
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001025 Bromo adjacent homology (BAH) domainDomainDomain
IPR001214 SET domainDomainDomain
IPR001487 BromodomainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003616 Post-SET domainDomainDomain
IPR006560 AWS domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017956 AT hook, DNA-binding motifSiteConserved site
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR043151 Bromo adjacent homology (BAH) domain superfamilyFamilyHomologous superfamily
IPR043319 ASH1-like, PHD fingerDomainDomain
IPR043320 ASH1-like, BromodomainDomainDomain

Diseases

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