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Entity Details
Primary name
IF4G3_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O43432
EntryName
IF4G3_HUMAN
FullName
Eukaryotic translation initiation factor 4 gamma 3
TaxID
9606
Evidence
evidence at protein level
Length
1585
SequenceStatus
complete
DateCreated
2004-06-07
DateModified
2021-06-02
Ontological Relatives
Genes
EIF4G3
GO terms
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GO
Name
GO:0000339
RNA cap binding
GO:0003723
RNA binding
GO:0003729
mRNA binding
GO:0003743
translation initiation factor activity
GO:0005829
cytosol
GO:0006446
regulation of translational initiation
GO:0008135
translation factor activity, RNA binding
GO:0016281
eukaryotic translation initiation factor 4F complex
Subcellular Location
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Domains
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Domain
Name
Category
Type
IPR003307
W2 domain
Domain
Domain
IPR003890
MIF4G-like, type 3
Domain
Domain
IPR003891
Initiation factor eIF-4 gamma, MA3
Domain
Domain
IPR016021
MIF4G-like domain superfamily
Family
Homologous superfamily
IPR016024
Armadillo-type fold
Family
Homologous superfamily
IPR037585
Eukaryotic translation initiation factor 4 gamma 3
Family
Family
Diseases
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Drugs
Show/Hide Table
Interactions
12 interactions
Interactor
Partner
Sources
Publications
Link
IF4G3_HUMAN
PABP1_HUMAN
BioGRID, HPRD, MINT
26344197
29395067
9857202
details
IF4G3_HUMAN
VAV2_HUMAN
BioGRID, IntAct
18654987
details
IF4G3_HUMAN
MKNK1_HUMAN
BioGRID, HPRD, MINT
10022874
21900206
9878069
details
IF4G3_HUMAN
HSPB1_HUMAN
BioGRID, IntAct
25277244
details
IF4G3_HUMAN
IF4E_HUMAN
BioGRID, DIP, HPRD, IntAct, MINT
20212144
21191102
24981860
26186194
26344197
28514442
9418880
details
IF4G3_HUMAN
DNLI4_HUMAN
BioGRID
22990118
details
IF4G3_HUMAN
NCBP1_HUMAN
IntAct
15361857
details
IF4G3_HUMAN
IF4A1_HUMAN
BioGRID, HPRD, IntAct
17353931
22939629
28514442
29395067
9418880
details
IF4G3_HUMAN
DISC1_HUMAN
IntAct
31413325
details
IF4G3_HUMAN
EIF3B_HUMAN
BioGRID
24981860
9418880
details
IF4G3_HUMAN
YTHD2_HUMAN
BioGRID
29395067
details
IF4G3_HUMAN
KCC1A_HUMAN
HPRD
14507913
details
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