Entity Details

Primary name CLCF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBD9
EntryNameCLCF1_HUMAN
FullNameCardiotrophin-like cytokine factor 1
TaxID9606
Evidenceevidence at protein level
Length225
SequenceStatuscomplete
DateCreated2004-12-07
DateModified2021-06-02

Ontological Relatives

GenesCLCF1

GO terms

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GOName
GO:0002639 positive regulation of immunoglobulin production
GO:0005102 signaling receptor binding
GO:0005125 cytokine activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005576 extracellular region
GO:0007166 cell surface receptor signaling pathway
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0019221 cytokine-mediated signaling pathway
GO:0030183 B cell differentiation
GO:0030890 positive regulation of B cell proliferation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043524 negative regulation of neuron apoptotic process
GO:0048295 positive regulation of isotype switching to IgE isotypes
GO:0048711 positive regulation of astrocyte differentiation
GO:0097058 CRLF-CLCF1 complex
GO:0097059 CNTFR-CLCF1 complex

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR010681 Plethodontid receptivity factor PRF/cardiotrophin-likeFamilyFamily

Diseases

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