Entity Details

Primary name PEMT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBM1
EntryNamePEMT_HUMAN
FullNamePhosphatidylethanolamine N-methyltransferase
TaxID9606
Evidenceevidence at protein level
Length199
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesPEMT

GO terms

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GOName
GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity
GO:0001835 blastocyst hatching
GO:0004608 phosphatidylethanolamine N-methyltransferase activity
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006656 phosphatidylcholine biosynthetic process
GO:0006686 sphingomyelin biosynthetic process
GO:0008285 negative regulation of cell population proliferation
GO:0008429 phosphatidylethanolamine binding
GO:0016021 integral component of membrane
GO:0031526 brush border membrane
GO:0031966 mitochondrial membrane
GO:0032259 methylation
GO:0033273 response to vitamin
GO:0042383 sarcolemma
GO:0042493 response to drug
GO:0043200 response to amino acid
GO:0043231 intracellular membrane-bounded organelle
GO:0045471 response to ethanol
GO:0046498 S-adenosylhomocysteine metabolic process
GO:0046500 S-adenosylmethionine metabolic process
GO:0050747 positive regulation of lipoprotein metabolic process
GO:0080101 phosphatidyl-N-dimethylethanolamine N-methyltransferase activity
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Mitochondrion membrane

Domains

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DomainNameCategoryType
IPR007318 Phospholipid methyltransferaseFamilyFamily
IPR024960 Phosphatidyl-N-methylethanolamine/Phosphatidylethanolamine N-methyltransferaseFamilyFamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
PEMT_HUMANSTOM_HUMANBioGRID, IntAct32296183 details
PEMT_HUMANAQP6_HUMANBioGRID, IntAct32296183 details
PEMT_HUMANOSTP_HUMANBioGRID22779921 details
PEMT_HUMANFCERG_HUMANBioGRID32296183 details