Entity Details

Primary name RNF14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBS8
EntryNameRNF14_HUMAN
FullNameE3 ubiquitin-protein ligase RNF14
TaxID9606
Evidenceevidence at protein level
Length474
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesRNF14

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0000209 protein polyubiquitination
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007165 signal transduction
GO:0016567 protein ubiquitination
GO:0019787 ubiquitin-like protein transferase activity
GO:0030521 androgen receptor signaling pathway
GO:0031624 ubiquitin conjugating enzyme binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0050681 androgen receptor binding
GO:0060765 regulation of androgen receptor signaling pathway
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR002867 IBR domainDomainDomain
IPR006575 RWD domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR016135 Ubiquitin-conjugating enzyme/RWD-likeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR031127 E3 ubiquitin ligase RBR familyFamilyFamily
IPR031128 E3 ubiquitin-protein ligase RNF14FamilyFamily
IPR044066 TRIAD supradomainDomainDomain

Diseases

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Interactions

33 interactions

InteractorPartnerSourcesPublicationsLink
RNF14_HUMANUBE2U_HUMANBioGRID, IntAct19690564 details
RNF14_HUMANUB2D1_HUMANBioGRID, IntAct19549727 25416956 details
RNF14_HUMANUB2D2_HUMANBioGRID, IntAct19549727 29643511 details
RNF14_HUMANUB2D3_HUMANBioGRID, IntAct19549727 details
RNF14_HUMANUB2E1_HUMANBioGRID, HPRD, IntAct11322894 19549727 details
RNF14_HUMANUB2E2_HUMANBioGRID, IntAct11322894 19549727 25224329 details
RNF14_HUMANUB2V1_HUMANBioGRID, IntAct19549727 details
RNF14_HUMANUB2D4_HUMANBioGRID, IntAct19549727 25416956 31515488 details
RNF14_HUMANUBE2W_HUMANBioGRID, IntAct19549727 details
RNF14_HUMANUB2E3_HUMANBioGRID, IntAct11322894 19549727 details
RNF14_HUMANANDR_HUMANBioGRID, HPRD, IntAct10085091 11673464 11779876 12612084 15604093 17082327 17110431 19345326 24422631 details
RNF14_HUMANPHF7_HUMANBioGRID, IntAct22493164 details
RNF14_HUMANHNF1A_HUMANBioGRID, MINT23449499 details
RNF14_HUMANDACH1_HUMANBioGRID, IntAct25416956 32296183 details
RNF14_HUMANGRN_HUMANIntAct32814053 details
RNF14_HUMANPRKN_HUMANIntAct32814053 details
RNF14_HUMANRNF11_HUMANIntAct32814053 details
RNF14_HUMANTADBP_HUMANIntAct32814053 details
RNF14_HUMANRNF14_HUMANBioGRID11322894 details
RNF14_HUMANVDR_HUMANBioGRID15805579 details
RNF14_HUMANROA1_HUMANBioGRID17110431 details
RNF14_HUMANTAGL_HUMANBioGRID17082327 details
RNF14_HUMANTNAP3_HUMANBioGRID23105109 details
RNF14_HUMANTET5A_HUMANBioGRID, HPRD15231748 details
RNF14_HUMANUB2L3_HUMANBioGRID29643511 details
RNF14_HUMANTFE2_HUMANBioGRID23449499 details
RNF14_HUMANLEF1_HUMANBioGRID23449499 details
RNF14_HUMANITF2_HUMANBioGRID23449499 details
RNF14_HUMANDET1_HUMANBioGRID17452440 details
RNF14_HUMANPLPL7_HUMANBioGRID26606397 details
RNF14_HUMANNCOA4_HUMANHPRD10085091 details
RNF14_HUMANESR1_HUMANHPRD10085091 details
RNF14_HUMANGCR_HUMANHPRD10085091 details