Entity Details

Primary name BIN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBW5
EntryNameBIN2_HUMAN
FullNameBridging integrator 2
TaxID9606
Evidenceevidence at protein level
Length565
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesBIN2

GO terms

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GOName
GO:0001891 phagocytic cup
GO:0002102 podosome
GO:0005543 phospholipid binding
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0006911 phagocytosis, engulfment
GO:0030054 cell junction
GO:0034774 secretory granule lumen
GO:0042995 cell projection
GO:0043312 neutrophil degranulation
GO:0060326 cell chemotaxis
GO:0071800 podosome assembly
GO:0097320 plasma membrane tubulation
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR003005 AmphiphysinFamilyFamily
IPR004148 BAR domainDomainDomain
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR028827 Bridging integrator 2FamilyFamily

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
BIN2_HUMANTERF1_HUMANbhf-ucl, BioGRID21044950 details
BIN2_HUMANTINF2_HUMANbhf-ucl, BioGRID21044950 details
BIN2_HUMANPOTE1_HUMANbhf-ucl, BioGRID21044950 details
BIN2_HUMANAPBP2_HUMANBioGRID, IntAct32296183 details
BIN2_HUMANBIN1_HUMANBioGRID, IntAct, UniProt10903846 28514442 details