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Entity Details
Primary name
AFF4_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9UHB7
EntryName
AFF4_HUMAN
FullName
AF4/FMR2 family member 4
TaxID
9606
Evidence
evidence at protein level
Length
1163
SequenceStatus
complete
DateCreated
2006-06-13
DateModified
2021-06-02
Ontological Relatives
Genes
AFF4
GO terms
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GO
Name
GO:0001650
fibrillar center
GO:0005654
nucleoplasm
GO:0006366
transcription by RNA polymerase II
GO:0006368
transcription elongation from RNA polymerase II promoter
GO:0007286
spermatid development
GO:0008023
transcription elongation factor complex
GO:0010468
regulation of gene expression
GO:0032783
super elongation complex
GO:0035327
transcriptionally active chromatin
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR007797
AF4/FMR2 family
Family
Family
IPR043639
AF4 interaction motif
Site
Conserved site
IPR043640
AF4/FMR2, C-terminal homology domain
Domain
Domain
Diseases
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Drugs
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Interactions
17 interactions
Interactor
Partner
Sources
Publications
Link
AFF4_HUMAN
ENL_HUMAN
BioGRID, HPRD, IntAct
15856011
20153263
20431927
21729782
21873227
25921070
26344197
details
AFF4_HUMAN
AF9_HUMAN
BioGRID, IntAct
20153263
20431927
20854876
21729782
21873227
25417107
details
AFF4_HUMAN
ELL2_HUMAN
BioGRID, IntAct
21729782
22483617
26186194
26496610
28514442
32296183
details
AFF4_HUMAN
SIAH1_HUMAN
BioGRID, HPRD, IntAct
16189514
25416956
details
AFF4_HUMAN
AP2B1_HUMAN
BioGRID, IntAct
25416956
details
AFF4_HUMAN
GOGA2_HUMAN
BioGRID, IntAct
25416956
details
AFF4_HUMAN
TRAF2_HUMAN
BioGRID, HPRD, IntAct
16189514
25416956
details
AFF4_HUMAN
MTUS2_HUMAN
BioGRID, IntAct
25416956
details
AFF4_HUMAN
SDCB1_HUMAN
MINT
26787460
details
AFF4_HUMAN
LRRK2_HUMAN
BioGRID, IntAct
29513927
details
AFF4_HUMAN
OSTP_HUMAN
BioGRID
22779921
details
AFF4_HUMAN
MED19_HUMAN
BioGRID, IntAct
15175163
21729782
details
AFF4_HUMAN
CDK9_HUMAN
BioGRID, HPRD, IntAct
12065898
17643375
20153263
21729782
21873227
22483617
23455922
23602568
26186194
27684187
28514442
32479599
details
AFF4_HUMAN
CCNT1_HUMAN
BioGRID, HPRD, IntAct
12065898
20153263
21729782
26186194
27684187
28514442
details
AFF4_HUMAN
FMR1_HUMAN
IntAct
31413325
details
AFF4_HUMAN
KMT2A_HUMAN
BioGRID
20153263
22094252
details
AFF4_HUMAN
UBP7_HUMAN
BioGRID
27934968
details
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