Entity Details

Primary name ZEB2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60315
EntryNameZEB2_HUMAN
FullNameZinc finger E-box-binding homeobox 2
TaxID9606
Evidenceevidence at protein level
Length1214
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesZEB2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0019208 phosphatase regulator activity
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0043565 sequence-specific DNA binding
GO:0045636 positive regulation of melanocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048023 positive regulation of melanin biosynthetic process
GO:0048066 developmental pigmentation
GO:0048856 anatomical structure development
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097324 melanocyte migration
GO:1903056 regulation of melanosome organization

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR008598 Drought induced 19 protein type, zinc-binding domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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