Entity Details

Primary name LFTY1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75610
EntryNameLFTY1_HUMAN
FullNameLeft-right determination factor 1
TaxID9606
Evidenceevidence at transcript level
Length366
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesLEFTY1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003007 heart morphogenesis
GO:0005125 cytokine activity
GO:0005160 transforming growth factor beta receptor binding
GO:0005615 extracellular space
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007368 determination of left/right symmetry
GO:0008083 growth factor activity
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030509 BMP signaling pathway
GO:0060395 SMAD protein signal transduction

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001111 TGF-beta, propeptideDomainDomain
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR003942 Left- Right determination factorFamilyFamily
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink