Entity Details

Primary name ERLN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94905
EntryNameERLN2_HUMAN
FullNameErlin-2
TaxID9606
Evidenceevidence at protein level
Length339
SequenceStatuscomplete
DateCreated2003-10-31
DateModified2021-06-02

Ontological Relatives

GenesERLIN2

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0008203 cholesterol metabolic process
GO:0015485 cholesterol binding
GO:0016021 integral component of membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0031625 ubiquitin protein ligase binding
GO:0032933 SREBP signaling pathway
GO:0032991 protein-containing complex
GO:0045121 membrane raft
GO:0045541 negative regulation of cholesterol biosynthetic process
GO:0045717 negative regulation of fatty acid biosynthetic process
GO:0055085 transmembrane transport

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001107 Band 7 domainDomainDomain
IPR033294 Erlin1/2FamilyFamily

Diseases

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Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
ERLN2_HUMANERLN1_HUMANBioGRID, IntAct, UniProt19240031 21343306 22119785 22690709 22939629 24217618 30021884 details
ERLN2_HUMANTCPB_HUMANBioGRID23190606 details
ERLN2_HUMANNICA_HUMANBioGRID, IntAct22771797 26496610 details
ERLN2_HUMANAMFR_HUMANBioGRID, IntAct, UniProt17502376 21343306 22119785 24217618 details
ERLN2_HUMANSYVN1_HUMANBioGRID, IntAct, UniProt17502376 21343306 22119785 details
ERLN2_HUMANRN139_HUMANBioGRID, UniProt21343306 details
ERLN2_HUMANINSI1_HUMANBioGRID, UniProt21343306 22690709 24217618 32322062 details
ERLN2_HUMANTMUB1_HUMANBioGRID, UniProt21343306 details
ERLN2_HUMANHMDH_HUMANBioGRID, UniProt17502376 21343306 details
ERLN2_HUMANSTOM_HUMANBioGRID, IntAct27173435 unassigned1312 details
ERLN2_HUMANRN170_HUMANBioGRID, IntAct25882839 28514442 32614325 details
ERLN2_HUMANPSN1_HUMANBioGRID, UniProt22771797 25959826 details
ERLN2_HUMANMBRL_HUMANBioGRID, IntAct22119785 32738194 details
ERLN2_HUMANRN185_HUMANBioGRID17558393 24019521 32614325 32738194 details
ERLN2_HUMANITPR1_HUMANBioGRID17502376 19240031 25882839 details
ERLN2_HUMANPSMD2_HUMANBioGRID17502376 details
ERLN2_HUMANUFD1_HUMANBioGRID17502376 details
ERLN2_HUMANDERL1_HUMANBioGRID17502376 details
ERLN2_HUMANCD3D_HUMANBioGRID17502376 details
ERLN2_HUMANFBX6_HUMANBioGRID22268729 32409323 details
ERLN2_HUMANSCAP_HUMANBioGRID22690709 24217618 details
ERLN2_HUMANAPH1A_HUMANBioGRID22771797 details
ERLN2_HUMANPEN2_HUMANBioGRID22771797 details
ERLN2_HUMANSRBP1_HUMANBioGRID24217618 details
ERLN2_HUMANSRBP2_HUMANBioGRID24217618 details
ERLN2_HUMANSEPR_HUMANBioGRID26209915 details
ERLN2_HUMANRNF5_HUMANBioGRID24019521 details
ERLN2_HUMANTBA1B_HUMANBioGRID27462423 details
ERLN2_HUMANCDK1_HUMANBioGRID27462423 details
ERLN2_HUMANCCNB1_HUMANBioGRID27462423 details
ERLN2_HUMANTM41B_HUMANBioGRID30352685 details