Entity Details

Primary name ATS2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95450
EntryNameATS2_HUMAN
FullNameA disintegrin and metalloproteinase with thrombospondin motifs 2
TaxID9606
Evidenceevidence at transcript level
Length1211
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesADAMTS2

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0007283 spermatogenesis
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016485 protein processing
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0030324 lung development
GO:0030574 collagen catabolic process
GO:0031012 extracellular matrix
GO:0043588 skin development
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR010294 ADAM-TS Spacer 1DomainDomain
IPR010909 PLACDomainDomain
IPR013273 ADAMTS/ADAMTS-likeFamilyFamily
IPR013275 Peptidase M12B, ADAM-TS2FamilyFamily
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR041645 ADAM cysteine-rich domain 2DomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ATS2_HUMANPI3R5_HUMANIntAct18624398 details
ATS2_HUMANP85A_HUMANBioGRID18624398 details