Entity Details

Primary name FGF19_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95750
EntryNameFGF19_HUMAN
FullNameFibroblast growth factor 19
TaxID9606
Evidenceevidence at protein level
Length216
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesFGF19

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007399 nervous system development
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009887 animal organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0046326 positive regulation of glucose import
GO:0046330 positive regulation of JNK cascade
GO:0051897 positive regulation of protein kinase B signaling
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070858 negative regulation of bile acid biosynthetic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028303 Fibroblast growth factor 15/19FamilyFamily
IPR035444 Fibroblast growth factor 15/19/21FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01109 HeparinDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FGF19_HUMANFGFR4_HUMANBioGRID, DIP, HPRD10525310 19706524 details
FGF19_HUMANFGFR1_HUMANDIP19706524 details