Entity Details

Primary name S1PR4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95977
EntryNameS1PR4_HUMAN
FullNameSphingosine 1-phosphate receptor 4
TaxID9606
Evidenceevidence at protein level
Length384
SequenceStatuscomplete
DateCreated2004-02-16
DateModified2021-06-02

Ontological Relatives

GenesS1PR4

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008289 lipid binding
GO:0019222 regulation of metabolic process
GO:0038036 sphingosine-1-phosphate receptor activity

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR004061 Sphingosine 1-phosphate receptorFamilyFamily
IPR004064 EDG-6 sphingosine 1-phosphate receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB08868 FingolimodDrugbanksmall molecule

Interactions

5 interactions