Entity Details

Primary name OAT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04181
EntryNameOAT_HUMAN
FullNameOrnithine aminotransferase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length439
SequenceStatuscomplete
DateCreated1987-03-20
DateModified2021-06-02

Ontological Relatives

GenesOAT

GO terms

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GOName
GO:0004587 ornithine-oxo-acid transaminase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0007601 visual perception
GO:0009064 glutamine family amino acid metabolic process
GO:0010121 arginine catabolic process to proline via ornithine
GO:0019544 arginine catabolic process to glutamate
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
GO:0050155 ornithine(lysine) transaminase activity
GO:0055129 L-proline biosynthetic process

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR005814 Aminotransferase class-IIIFamilyFamily
IPR010164 Ornithine aminotransferaseFamilyFamily
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00129 OrnithineDrugbanksmall molecule
DB02054 GabaculineDrugbanksmall molecule
DB02821 CanalineDrugbanksmall molecule