Entity Details

Primary name FCG3A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08637
EntryNameFCG3A_HUMAN
FullNameLow affinity immunoglobulin gamma Fc region receptor III-A
TaxID9606
Evidenceevidence at protein level
Length254
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesFCGR3A

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004888 transmembrane signaling receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0018149 peptide cross-linking
GO:0019864 IgG binding
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0050776 regulation of immune response
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00002 CetuximabDrugbankbiotech
DB00005 EtanerceptDrugbankbiotech
DB00028 Human immunoglobulin GDrugbankbiotech
DB00056 Gemtuzumab ozogamicinDrugbankbiotech
DB00087 AlemtuzumabDrugbankbiotech
DB00092 AlefaceptDrugbankbiotech
DB00110 PalivizumabDrugbankbiotech
DB00111 DaclizumabDrugbankbiotech
DB00112 BevacizumabDrugbankbiotech
DB06607 CatumaxomabDrugbankbiotech
DB11767 SarilumabDrugbankbiotech
DB12023 BenralizumabDrugbankbiotech