Entity Details

Primary name GNAT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11488
EntryNameGNAT1_HUMAN
FullNameGuanine nucleotide-binding protein G(t) subunit alpha-1
TaxID9606
Evidenceevidence at protein level
Length350
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesGNAT1

GO terms

Show/Hide Table
GOName
GO:0000035 acyl binding
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0001664 G protein-coupled receptor binding
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005829 cytosol
GO:0005834 heterotrimeric G-protein complex
GO:0005886 plasma membrane
GO:0006457 protein folding
GO:0007165 signal transduction
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007601 visual perception
GO:0007603 phototransduction, visible light
GO:0008283 cell population proliferation
GO:0009416 response to light stimulus
GO:0009642 response to light intensity
GO:0016020 membrane
GO:0016056 rhodopsin mediated signaling pathway
GO:0016324 apical plasma membrane
GO:0019003 GDP binding
GO:0019901 protein kinase binding
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0032391 photoreceptor connecting cilium
GO:0042462 eye photoreceptor cell development
GO:0042622 photoreceptor outer segment membrane
GO:0043025 neuronal cell body
GO:0046872 metal ion binding
GO:0050908 detection of light stimulus involved in visual perception
GO:0050917 sensory perception of umami taste
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity
GO:0060041 retina development in camera-type eye
GO:0071257 cellular response to electrical stimulus
GO:0097381 photoreceptor disc membrane

Subcellular Location

Show/Hide Table
Subcellular Location
Cell projection
Membrane
Photoreceptor inner segment

Domains

Show/Hide Table
DomainNameCategoryType
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunitFamilyFamily
IPR001408 G-protein alpha subunit, group IFamilyFamily
IPR011025 G protein alpha subunit, helical insertionFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB02994 Cacodylic acidDrugbanksmall molecule
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule
DB04444 Tetrafluoroaluminate IonDrugbanksmall molecule