Entity Details

Primary name HNRPL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP14866
EntryNameHNRPL_HUMAN
FullNameHeterogeneous nuclear ribonucleoprotein L
TaxID9606
Evidenceevidence at protein level
Length589
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesHNRNPL

GO terms

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GOName
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000398 mRNA splicing, via spliceosome
GO:0000976 transcription cis-regulatory region binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006396 RNA processing
GO:0016020 membrane
GO:0016070 RNA metabolic process
GO:0035770 ribonucleoprotein granule
GO:0043484 regulation of RNA splicing
GO:0070062 extracellular exosome
GO:0097157 pre-mRNA intronic binding
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR006536 HnRNP-L/PTBFamilyFamily
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR021790 PTBP1, RNA recognition motif 2-likeDomainDomain
IPR034816 hnRNP-L, RNA recognition motif 3DomainDomain
IPR034817 hnRNP-L, RNA recognition motif 4DomainDomain
IPR035005 hnRNP-L, RNA recognition motif 1DomainDomain
IPR035008 hnRNP-L, RNA recognition motif 2DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB09130 CopperDrugbanksmall molecule

Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
HNRPL_HUMANXPO2_HUMANBioGRID, HPRD, IntAct16169070 26344197 details
HNRPL_HUMANHMGA1_HUMANBioGRID, IntAct18850631 details
HNRPL_HUMANFGFR3_HUMANBioGRID, HPRD, IntAct16169070 details
HNRPL_HUMANPCBP2_HUMANBioGRID, HPRD, MINT10772858 21623344 8871564 details
HNRPL_HUMANHM20B_HUMANBioGRID, HPRD, IntAct16169070 details
HNRPL_HUMANROA2_HUMANBioGRID, DIP, HPRD10441480 22939629 23976881 28611215 details
HNRPL_HUMANPJA1_HUMANHPRD, IntAct16169070 details
HNRPL_HUMANPTBP1_HUMANBioGRID, HPRD10772858 22939629 26344197 9563502 details
HNRPL_HUMANCSK21_HUMANBioGRID, IntAct22113938 details
HNRPL_HUMANHNRPK_HUMANBioGRID, HPRD10772858 22939629 26344197 details
HNRPL_HUMANITCH_HUMANBioGRID16055720 28611215 details
HNRPL_HUMANILF3_HUMANBioGRID, DIP23976881 details
HNRPL_HUMANOGT1_HUMANBioGRID28611215 32994395 details
HNRPL_HUMANHNRPL_HUMANBioGRID, HPRD10772858 details
HNRPL_HUMANCBP_HUMANBioGRID28611215 32238831 details
HNRPL_HUMANAPEX1_HUMANBioGRID, HPRD11809897 28986522 details
HNRPL_HUMANNEDD4_HUMANBioGRID16055720 details
HNRPL_HUMANH31T_HUMANBioGRID20850016 details
HNRPL_HUMANSUMO2_HUMANBioGRID32786267 details
HNRPL_HUMANDFFA_HUMANIntAct17353931 details
HNRPL_HUMANZNRD2_HUMANIntAct17353931 details
HNRPL_HUMANLFG4_HUMANIntAct17353931 details
HNRPL_HUMANTNR14_HUMANIntAct17353931 details
HNRPL_HUMANSGK1_HUMANIntAct17353931 details
HNRPL_HUMANTRAF6_HUMANIntAct17353931 details
HNRPL_HUMANSMYD2_HUMANIntAct17353931 details
HNRPL_HUMANSRRM2_HUMANBioGRID16159877 details
HNRPL_HUMANILK_HUMANIntAct17353931 details
HNRPL_HUMANCFLAR_HUMANIntAct17353931 details
HNRPL_HUMANTOPRS_HUMANBioGRID17803295 details
HNRPL_HUMANSMRCD_HUMANBioGRID21549307 details
HNRPL_HUMANRARA_HUMANIntAct17353931 details
HNRPL_HUMANVHL_HUMANBioGRID, DIP21942715 23976881 details
HNRPL_HUMANHDAC5_HUMANBioGRID21081666 details
HNRPL_HUMANMBNL1_HUMANBioGRID21900255 28611215 details
HNRPL_HUMANISG15_HUMANBioGRID16009940 33024031 details
HNRPL_HUMANDAB2_HUMANBioGRID22323290 details
HNRPL_HUMANITA4_HUMANBioGRID22623428 details
HNRPL_HUMANU2AF2_HUMANBioGRID26641092 28611215 details
HNRPL_HUMANPABP1_HUMANBioGRID29395067 details
HNRPL_HUMANPSA3_HUMANBioGRID30009671 details
HNRPL_HUMANNS1BP_HUMANBioGRID23825951 details
HNRPL_HUMANAKTIP_HUMANBioGRID27512140 details
HNRPL_HUMANXRN2_HUMANBioGRID29395067 details
HNRPL_HUMANSOX2_HUMANBioGRID21280222 details
HNRPL_HUMANEIF3H_HUMANBioGRID32269044 details
HNRPL_HUMANIF2B3_HUMANBioGRID29212181 details
HNRPL_HUMANRBM45_HUMANBioGRID26979993 details
HNRPL_HUMANSUMO4_HUMANHPRD16236267 details