Entity Details

Primary name KCNA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP16389
EntryNameKCNA2_HUMAN
FullNamePotassium voltage-gated channel subfamily A member 2
TaxID9606
Evidenceevidence at protein level
Length499
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesKCNA2

GO terms

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GOName
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005267 potassium channel activity
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006813 potassium ion transport
GO:0008076 voltage-gated potassium channel complex
GO:0014059 regulation of dopamine secretion
GO:0016021 integral component of membrane
GO:0019228 neuronal action potential
GO:0019233 sensory perception of pain
GO:0030027 lamellipodium
GO:0030424 axon
GO:0030425 dendrite
GO:0031258 lamellipodium membrane
GO:0032809 neuronal cell body membrane
GO:0033010 paranodal junction
GO:0034765 regulation of ion transmembrane transport
GO:0042734 presynaptic membrane
GO:0043204 perikaryon
GO:0043679 axon terminus
GO:0044224 juxtaparanode region of axon
GO:0051260 protein homooligomerization
GO:0071805 potassium ion transmembrane transport

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Endoplasmic reticulum membrane
Membrane

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR003131 Potassium channel tetramerisation-type BTB domainDomainDomain
IPR003968 Potassium channel, voltage dependent, KvFamilyFamily
IPR003972 Potassium channel, voltage dependent, Kv1FamilyFamily
IPR004049 Potassium channel, voltage dependent, Kv1.2FamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028325 Voltage-gated potassium channelFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB06637 DalfampridineDrugbanksmall molecule