Entity Details

Primary name KCNA4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22459
EntryNameKCNA4_HUMAN
FullNamePotassium voltage-gated channel subfamily A member 4
TaxID9606
Evidenceevidence at protein level
Length653
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesKCNA4

GO terms

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GOName
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006813 potassium ion transport
GO:0008076 voltage-gated potassium channel complex
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0030955 potassium ion binding
GO:0034765 regulation of ion transmembrane transport
GO:0043197 dendritic spine
GO:0051260 protein homooligomerization
GO:0071805 potassium ion transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR003131 Potassium channel tetramerisation-type BTB domainDomainDomain
IPR003968 Potassium channel, voltage dependent, KvFamilyFamily
IPR003972 Potassium channel, voltage dependent, Kv1FamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR012897 Potassium channel, voltage dependent, Kv1.4, tandem inactivation domainDomainDomain
IPR020467 Potassium channel, voltage dependent, Kv1.4FamilyFamily
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028325 Voltage-gated potassium channelFamilyFamily
IPR037065 Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB02299 ArginineamideDrugbanksmall molecule
DB06637 DalfampridineDrugbanksmall molecule