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Entity Details
Primary name
S10A4_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P26447
EntryName
S10A4_HUMAN
FullName
Protein S100-A4
TaxID
9606
Evidence
evidence at protein level
Length
101
SequenceStatus
complete
DateCreated
1992-08-01
DateModified
2021-06-02
Ontological Relatives
Genes
S100A4
GO terms
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GO
Name
GO:0001837
epithelial to mesenchymal transition
GO:0003723
RNA binding
GO:0003779
actin binding
GO:0005509
calcium ion binding
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005634
nucleus
GO:0042802
identical protein binding
GO:0043005
neuron projection
GO:0043123
positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046914
transition metal ion binding
GO:0048306
calcium-dependent protein binding
GO:0048471
perinuclear region of cytoplasm
GO:0050786
RAGE receptor binding
GO:0062023
collagen-containing extracellular matrix
GO:0070062
extracellular exosome
Subcellular Location
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Subcellular Location
Cytoplasm
Nucleus
Secreted
Domains
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Domain
Name
Category
Type
IPR001751
S100/Calbindin-D9k, conserved site
Site
Conserved site
IPR002048
EF-hand domain
Domain
Domain
IPR011992
EF-hand domain pair
Family
Homologous superfamily
IPR013787
S100/CaBP-9k-type, calcium binding, subdomain
Domain
Domain
IPR018247
EF-Hand 1, calcium-binding site
Site
Binding site
IPR028496
Protein S100-A4
Family
Family
IPR034325
S-100
Domain
Domain
Diseases
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Drugs
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Drug
Name
Source
Type
DB00831
Trifluoperazine
Drugbank
small molecule
DB09130
Copper
Drugbank
small molecule
Interactions
44 interactions
Interactor
Partner
Sources
Publications
Link
S10A4_HUMAN
BAG6_HUMAN
BioGRID, HPRD, IntAct
16169070
details
S10A4_HUMAN
U119A_HUMAN
BioGRID, HPRD, IntAct
16169070
details
S10A4_HUMAN
S10A1_HUMAN
BioGRID, HPRD, IntAct
10753920
10869553
15608682
16189514
32296183
9926943
details
S10A4_HUMAN
AREG_HUMAN
MINT, UniProt
19740107
30083275
details
S10A4_HUMAN
HBEGF_HUMAN
MINT
19740107
details
S10A4_HUMAN
P53_HUMAN
BioGRID, HPRD, IntAct, MINT, UniProt
11278647
11527429
12942774
15116098
19740107
20070253
20591429
23752197
31837246
details
S10A4_HUMAN
EGF_HUMAN
MINT
19740107
details
S10A4_HUMAN
BTC_HUMAN
MINT
19740107
details
S10A4_HUMAN
MDM2_HUMAN
BioGRID, MINT
20591429
details
S10A4_HUMAN
S100B_HUMAN
BioGRID, IntAct, MINT
21516116
25416956
26496610
32296183
details
S10A4_HUMAN
HSPB1_HUMAN
BioGRID, IntAct
25277244
details
S10A4_HUMAN
EGFR_HUMAN
BioGRID, IntAct, UniProt
24658140
25402006
30083275
31980649
details
S10A4_HUMAN
S10A4_HUMAN
DIP, HPRD
11278510
11994292
12756252
20421509
22483112
details
S10A4_HUMAN
MYH9_HUMAN
DIP, HPRD, UniProt
15289939
20421509
22460785
22483112
31837246
9405067
details
S10A4_HUMAN
ERBB3_HUMAN
UniProt
30083275
details
S10A4_HUMAN
ERBB4_HUMAN
UniProt
30083275
details
S10A4_HUMAN
NRG1_HUMAN
UniProt
30083275
details
S10A4_HUMAN
RAGE_HUMAN
UniProt
30083275
details
S10A4_HUMAN
NAC1_HUMAN
UniProt
31837246
details
S10A4_HUMAN
CYBP_HUMAN
UniProt
31837246
details
S10A4_HUMAN
CEP20_HUMAN
BioGRID, UniProt
28765046
31837246
details
S10A4_HUMAN
TRPM4_HUMAN
UniProt
31837246
details
S10A4_HUMAN
EZRI_HUMAN
UniProt
31837246
details
S10A4_HUMAN
KS6A1_HUMAN
UniProt
31837246
details
S10A4_HUMAN
SMAD3_HUMAN
BioGRID
20070253
details
S10A4_HUMAN
SRPK2_HUMAN
BioGRID
26167880
details
S10A4_HUMAN
RHOU_HUMAN
BioGRID
26598620
details
S10A4_HUMAN
CCN3_HUMAN
BioGRID, HPRD
12147716
14606958
details
S10A4_HUMAN
FCG3A_HUMAN
BioGRID
23024279
details
S10A4_HUMAN
MAP2_HUMAN
HPRD
11994292
details
S10A4_HUMAN
S100P_HUMAN
HPRD
15171681
details
S10A4_HUMAN
LIPB1_HUMAN
BioGRID, HPRD
11836260
details
S10A4_HUMAN
SMAD2_HUMAN
BioGRID
20070253
details
S10A4_HUMAN
RHOA_HUMAN
BioGRID
26825171
details
S10A4_HUMAN
TPM3_HUMAN
HPRD
8120097
details
S10A4_HUMAN
SEPT2_HUMAN
HPRD
14531065
details
S10A4_HUMAN
SEPT7_HUMAN
HPRD
14531065
details
S10A4_HUMAN
SEPT6_HUMAN
HPRD
14531065
details
S10A4_HUMAN
MYH4_HUMAN
HPRD
14640694
9405067
details
S10A4_HUMAN
TPM2_HUMAN
HPRD
8120097
details
S10A4_HUMAN
ACTS_HUMAN
HPRD
14640694
details
S10A4_HUMAN
ANXA2_HUMAN
HPRD
15788416
details
S10A4_HUMAN
MYH2_HUMAN
HPRD
12756252
details
S10A4_HUMAN
MYH10_HUMAN
HPRD
9405067
details
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