Entity Details

Primary name GBRR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28476
EntryNameGBRR2_HUMAN
FullNameGamma-aminobutyric acid receptor subunit rho-2
TaxID9606
Evidenceevidence at transcript level
Length465
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesGABRR2

GO terms

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GOName
GO:0004890 GABA-A receptor activity
GO:0005254 chloride channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007601 visual perception
GO:0019904 protein domain specific binding
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0034707 chloride channel complex
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0050877 nervous system process
GO:0098982 GABA-ergic synapse
GO:1902476 chloride transmembrane transport
GO:1902711 GABA-A receptor complex
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alphaFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR008057 Gamma-aminobutyric-acid A receptor, RhoFamilyFamily
IPR008059 Gamma-aminobutyric-acid A receptor, Rho2FamilyFamily
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01567 FludiazepamDrugbanksmall molecule