Entity Details

Primary name SC6A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30531
EntryNameSC6A1_HUMAN
FullNameSodium- and chloride-dependent GABA transporter 1
TaxID9606
Evidenceevidence at protein level
Length599
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesSLC6A1

GO terms

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GOName
GO:0005332 gamma-aminobutyric acid:sodium symporter activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007268 chemical synaptic transmission
GO:0007613 memory
GO:0008306 associative learning
GO:0009986 cell surface
GO:0010035 response to inorganic substance
GO:0015185 gamma-aminobutyric acid transmembrane transporter activity
GO:0015378 sodium:chloride symporter activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0035725 sodium ion transmembrane transport
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0046872 metal ion binding
GO:0050808 synapse organization
GO:0051936 gamma-aminobutyric acid reuptake
GO:0051939 gamma-aminobutyric acid import
GO:0098658 inorganic anion import across plasma membrane
GO:0098719 sodium ion import across plasma membrane
GO:0098793 presynapse
GO:0150104 transport across blood-brain barrier
GO:1902476 chloride transmembrane transport

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR000175 Sodium:neurotransmitter symporterFamilyFamily
IPR002980 Sodium:neurotransmitter symporter, GABA, GAT-1FamilyFamily
IPR037272 Sodium:neurotransmitter symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00349 ClobazamDrugbanksmall molecule
DB00906 TiagabineDrugbanksmall molecule
DB08848 GuvacineDrugbanksmall molecule