Entity Details

Primary name HXD3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31249
EntryNameHXD3_HUMAN
FullNameHomeobox protein Hox-D3
TaxID9606
Evidenceevidence at protein level
Length432
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesHOXD3

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007160 cell-matrix adhesion
GO:0007219 Notch signaling pathway
GO:0009952 anterior/posterior pattern specification
GO:0010628 positive regulation of gene expression
GO:0016235 aggresome
GO:0016604 nuclear body
GO:0021615 glossopharyngeal nerve morphogenesis
GO:0030878 thyroid gland development
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048704 embryonic skeletal system morphogenesis
GO:0051216 cartilage development
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001827 Homeobox protein, antennapedia type, conserved siteSiteConserved site
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain
IPR025281 Domain of unknown function DUF4074DomainDomain

Diseases

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Interactions

7 interactions