Entity Details

Primary name HNF1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35680
EntryNameHNF1B_HUMAN
FullNameHepatocyte nuclear factor 1-beta
TaxID9606
Evidenceevidence at protein level
Length557
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesHNF1B

GO terms

Show/Hide Table
GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001822 kidney development
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009743 response to carbohydrate
GO:0014070 response to organic cyclic compound
GO:0030073 insulin secretion
GO:0031016 pancreas development
GO:0031018 endocrine pancreas development
GO:0032922 circadian regulation of gene expression
GO:0035565 regulation of pronephros size
GO:0039020 pronephric nephron tubule development
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0044877 protein-containing complex binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048598 embryonic morphogenesis
GO:0048793 pronephros development
GO:0048806 genitalia development
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
GO:0065004 protein-DNA complex assembly
GO:0070365 hepatocyte differentiation

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR006897 Hepatocyte nuclear factor 1, beta isoform, C-terminalDomainDomain
IPR006899 Hepatocyte nuclear factor 1, N-terminalDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR010982 Lambda repressor-like, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR023219 Hepatocyte nuclear factor 1, N-terminal domain superfamilyFamilyHomologous superfamily
IPR039066 Hepatocyte nuclear factor 1FamilyFamily

Diseases

Show/Hide Table