Entity Details

Primary name SOX18_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35713
EntryNameSOX18_HUMAN
FullNameTranscription factor SOX-18
TaxID9606
Evidenceevidence at protein level
Length384
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesSOX18

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001701 in utero embryonic development
GO:0001942 hair follicle development
GO:0001944 vasculature development
GO:0001946 lymphangiogenesis
GO:0001947 heart looping
GO:0003151 outflow tract morphogenesis
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006355 regulation of transcription, DNA-templated
GO:0009653 anatomical structure morphogenesis
GO:0022405 hair cycle process
GO:0030154 cell differentiation
GO:0035050 embryonic heart tube development
GO:0043534 blood vessel endothelial cell migration
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048469 cell maturation
GO:0048866 stem cell fate specification
GO:0060214 endocardium formation
GO:0060836 lymphatic endothelial cell differentiation
GO:0060956 endocardial cell differentiation
GO:0061028 establishment of endothelial barrier
GO:0072091 regulation of stem cell proliferation
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR021934 Sox, C-terminalDomainDomain
IPR033392 Sox 7/17/18, central domainDomainDomain
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

5 interactions