Entity Details

Primary name TYRP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP40126
EntryNameTYRP2_HUMAN
FullNameL-dopachrome tautomerase
TaxID9606
Evidenceevidence at protein level
Length519
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesDCT

GO terms

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GOName
GO:0002052 positive regulation of neuroblast proliferation
GO:0004167 dopachrome isomerase activity
GO:0005507 copper ion binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006583 melanin biosynthetic process from tyrosine
GO:0008544 epidermis development
GO:0009637 response to blue light
GO:0016021 integral component of membrane
GO:0016491 oxidoreductase activity
GO:0021847 ventricular zone neuroblast division
GO:0033162 melanosome membrane
GO:0042438 melanin biosynthetic process
GO:0042470 melanosome
GO:0043231 intracellular membrane-bounded organelle
GO:0048066 developmental pigmentation
GO:0048468 cell development

Subcellular Location

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Subcellular Location
Melanosome
Melanosome membrane

Domains

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DomainNameCategoryType
IPR002227 Tyrosinase copper-binding domainDomainDomain
IPR008922 Uncharacterised domain, di-copper centreFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TYRP2_HUMANMYPR_HUMANBioGRID, IntAct32296183 details
TYRP2_HUMANTYRP2_HUMANBioGRID, HPRD10079069 9356298 details