Entity Details

Primary name PTGDS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP41222
EntryNamePTGDS_HUMAN
FullNameProstaglandin-H2 D-isomerase
TaxID9606
Evidenceevidence at protein level
Length190
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesPTGDS

GO terms

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GOName
GO:0001516 prostaglandin biosynthetic process
GO:0004667 prostaglandin-D synthase activity
GO:0005501 retinoid binding
GO:0005504 fatty acid binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005789 endoplasmic reticulum membrane
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0019371 cyclooxygenase pathway
GO:0031965 nuclear membrane
GO:0036094 small molecule binding
GO:0043303 mast cell degranulation
GO:0045187 regulation of circadian sleep/wake cycle, sleep
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Golgi apparatus
Nucleus membrane
Rough endoplasmic reticulum
Secreted

Domains

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DomainNameCategoryType
IPR000566 Lipocalin/cytosolic fatty-acid binding domainDomainDomain
IPR002345 LipocalinFamilyFamily
IPR002972 Prostaglandin D synthaseFamilyFamily
IPR012674 CalycinFamilyHomologous superfamily
IPR022272 Lipocalin family conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00162 Vitamin ADrugbanksmall molecule