Entity Details

Primary name SOX3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP41225
EntryNameSOX3_HUMAN
FullNameTranscription factor SOX-3
TaxID9606
Evidenceevidence at protein level
Length446
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesSOX3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0007417 central nervous system development
GO:0007423 sensory organ development
GO:0007530 sex determination
GO:0009653 anatomical structure morphogenesis
GO:0021854 hypothalamus development
GO:0021983 pituitary gland development
GO:0030154 cell differentiation
GO:0045665 negative regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060324 face development
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR022097 Transcription factor SOXFamilyFamily
IPR029550 Transcription factor SOX-3FamilyFamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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