Entity Details

Primary name PE2R2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP43116
EntryNamePE2R2_HUMAN
FullNameProstaglandin E2 receptor EP2 subtype
TaxID9606
Evidenceevidence at transcript level
Length358
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTGER2

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004957 prostaglandin E receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0071380 cellular response to prostaglandin E stimulus
GO:1904346 positive regulation of gastric mucosal blood circulation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001923 Prostanoid EP2 receptorFamilyFamily
IPR008365 Prostanoid receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00770 AlprostadilDrugbanksmall molecule
DB00917 DinoprostoneDrugbanksmall molecule
DB00929 MisoprostolDrugbanksmall molecule
DB08964 GemeprostDrugbanksmall molecule
DB09211 LimaprostDrugbanksmall molecule