Entity Details

Primary name KCNJ1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48048
EntryNameKCNJ1_HUMAN
FullNameATP-sensitive inward rectifier potassium channel 1
TaxID9606
Evidenceevidence at protein level
Length391
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesKCNJ1

GO terms

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GOName
GO:0005242 inward rectifier potassium channel activity
GO:0005524 ATP binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005886 plasma membrane
GO:0006813 potassium ion transport
GO:0007588 excretion
GO:0008076 voltage-gated potassium channel complex
GO:0015272 ATP-activated inward rectifier potassium channel activity
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
GO:1990573 potassium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003268 Potassium channel, inwardly rectifying, Kir1.1FamilyFamily
IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmicFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR016449 Potassium channel, inwardly rectifying, KirFamilyFamily
IPR040445 Potassium channel, inwardly rectifying, transmembrane domainDomainDomain
IPR041647 Inward rectifier potassium channel, C-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00217 BethanidineDrugbanksmall molecule
DB00222 GlimepirideDrugbanksmall molecule
DB00350 MinoxidilDrugbanksmall molecule
DB00414 AcetohexamideDrugbanksmall molecule
DB01124 TolbutamideDrugbanksmall molecule
DB01382 GlymidineDrugbanksmall molecule
DB01392 YohimbineDrugbanksmall molecule
DB08838 AgmatineDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule