Entity Details

Primary name TCPE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48643
EntryNameTCPE_HUMAN
FullNameT-complex protein 1 subunit epsilon
TaxID9606
Evidenceevidence at protein level
Length541
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesCCT5

GO terms

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GOName
GO:0003730 mRNA 3'-UTR binding
GO:0005524 ATP binding
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005832 chaperonin-containing T-complex
GO:0005874 microtubule
GO:0006457 protein folding
GO:0007339 binding of sperm to zona pellucida
GO:0009615 response to virus
GO:0016887 ATP hydrolysis activity
GO:0031681 G-protein beta-subunit binding
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0044183 protein folding chaperone
GO:0044297 cell body
GO:0048027 mRNA 5'-UTR binding
GO:0048487 beta-tubulin binding
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:0070062 extracellular exosome
GO:1901998 toxin transport
GO:1904851 positive regulation of establishment of protein localization to telomere
GO:1904871 positive regulation of protein localization to Cajal body
GO:1904874 positive regulation of telomerase RNA localization to Cajal body

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002194 Chaperonin TCP-1, conserved siteSiteConserved site
IPR002423 Chaperonin Cpn60/TCP-1 familyFamilyFamily
IPR012718 T-complex protein 1, epsilon subunitFamilyFamily
IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)FamilyFamily
IPR027409 GroEL-like apical domain superfamilyFamilyHomologous superfamily
IPR027410 TCP-1-like chaperonin intermediate domain superfamilyFamilyHomologous superfamily
IPR027413 GroEL-like equatorial domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

80 interactions

InteractorPartnerSourcesPublicationsLink
TCPE_HUMANELP1_HUMANBioGRID, HPRD, IntAct16169070 details
TCPE_HUMANXRN1_HUMANBioGRID, HPRD, IntAct15231747 details
TCPE_HUMANP53_HUMANBioGRID, HPRD, IntAct, MINT16169070 22653443 23443559 25144556 31152661 details
TCPE_HUMANMIC60_HUMANBioGRID, HPRD, IntAct16169070 details
TCPE_HUMANTBC17_HUMANBioGRID, HPRD, IntAct16169070 details
TCPE_HUMANZNRD2_HUMANBioGRID, HPRD, IntAct16189514 22939629 25416956 32296183 details
TCPE_HUMANHDAC3_HUMANBioGRID, HPRD, IntAct12502735 23752268 details
TCPE_HUMANOGT1_HUMANBioGRID, IntAct27705803 32994395 details
TCPE_HUMANHXA1_HUMANIntAct32814053 details
TCPE_HUMANPIAS1_HUMANIntAct32814053 details
TCPE_HUMANTIM8A_HUMANIntAct32814053 details
TCPE_HUMANWWP2_HUMANIntAct32814053 details
TCPE_HUMANNPFF_HUMANIntAct32814053 details
TCPE_HUMANHXK3_HUMANIntAct32814053 details
TCPE_HUMANSTABP_HUMANIntAct32814053 details
TCPE_HUMANCSN3_HUMANIntAct32814053 details
TCPE_HUMANBAG3_HUMANIntAct32814053 details
TCPE_HUMANBECN1_HUMANIntAct32814053 details
TCPE_HUMANSTAM2_HUMANIntAct32814053 details
TCPE_HUMANFBXL2_HUMANIntAct32814053 details
TCPE_HUMANVDAC2_HUMANIntAct32814053 details
TCPE_HUMANGCP4_HUMANIntAct32814053 details
TCPE_HUMANLONF2_HUMANIntAct32814053 details
TCPE_HUMANGFOD1_HUMANIntAct32814053 details
TCPE_HUMANSHOX2_HUMANIntAct32814053 details
TCPE_HUMANHYPM_HUMANIntAct32814053 details
TCPE_HUMANZN641_HUMANIntAct32814053 details
TCPE_HUMANLHX8_HUMANIntAct32814053 details
TCPE_HUMANKT33B_HUMANIntAct32814053 details
TCPE_HUMANCL074_HUMANIntAct32814053 details
TCPE_HUMANSEM4G_HUMANIntAct32814053 details
TCPE_HUMANRNF38_HUMANIntAct32814053 details
TCPE_HUMANARFG3_HUMANIntAct32814053 details
TCPE_HUMANCSN7B_HUMANIntAct32814053 details
TCPE_HUMANESRP1_HUMANIntAct32814053 details
TCPE_HUMANPGRP3_HUMANIntAct32814053 details
TCPE_HUMANSPAG8_HUMANIntAct32814053 details
TCPE_HUMANPHLP_HUMANBioGRID, HPRD15889144 details
TCPE_HUMANTHEG_HUMANBioGRID, HPRD10747865 details
TCPE_HUMANHD_HUMANIntAct32814053 details
TCPE_HUMANUBE2W_HUMANIntAct32814053 details
TCPE_HUMANCDC20_HUMANBioGRID23443559 25306918 26811472 28096334 details
TCPE_HUMANATX1_HUMANIntAct32814053 details
TCPE_HUMANERCC6_HUMANBioGRID31722399 details
TCPE_HUMANSUMO2_HUMANBioGRID32786267 details
TCPE_HUMANTERT_HUMANBioGRID23741361 details
TCPE_HUMANMCPH1_HUMANBioGRID29150431 details
TCPE_HUMANERPG3_HUMANBioGRID31722399 details
TCPE_HUMANIKKE_HUMANBioGRID, IntAct14743216 25852190 details
TCPE_HUMANM3K1_HUMANIntAct14743216 details
TCPE_HUMANTBK1_HUMANIntAct14743216 details
TCPE_HUMANM3K3_HUMANIntAct14743216 details
TCPE_HUMANTCPA_HUMANBioGRID, HPRD, IntAct16085932 16097032 22939629 26344197 9250675 details
TCPE_HUMANDCAF7_HUMANBioGRID, IntAct25342745 27705803 28514442 details
TCPE_HUMANRIPK3_HUMANIntAct14743216 details
TCPE_HUMANACTA_HUMANBioGRID, HPRD11580270 details
TCPE_HUMANSRRM1_HUMANBioGRID16159877 details
TCPE_HUMANRGS7_HUMANBioGRID19376773 details
TCPE_HUMANFGF11_HUMANBioGRID28027390 details
TCPE_HUMANF86B2_HUMANBioGRID23349634 details
TCPE_HUMAN2ABA_HUMANBioGRID19156129 details
TCPE_HUMANACTB_HUMANBioGRID, HPRD11580269 details
TCPE_HUMANVHL_HUMANBioGRID17339318 21942715 details
TCPE_HUMANSIR6_HUMANBioGRID24169447 details
TCPE_HUMANGNB5_HUMANBioGRID19376773 details
TCPE_HUMANSMAP2_HUMANBioGRID29395067 details
TCPE_HUMANGAN_HUMANBioGRID26460568 details
TCPE_HUMANACTS_HUMANBioGRID, HPRD11580270 details
TCPE_HUMANNLE1_HUMANBioGRID26472760 details
TCPE_HUMANHEY1_HUMANBioGRID27129302 details
TCPE_HUMANCOP1_HUMANBioGRID16497536 details
TCPE_HUMANSRRM2_HUMANBioGRID16159877 details
TCPE_HUMANWDR82_HUMANBioGRID20516061 details
TCPE_HUMANHDAC5_HUMANBioGRID21081666 details
TCPE_HUMANGBB1_HUMANBioGRID19376773 details
TCPE_HUMANPACRG_HUMANBioGRID14532270 details
TCPE_HUMANEFMT3_HUMANBioGRID23349634 details
TCPE_HUMANTTC27_HUMANBioGRID26472760 details
TCPE_HUMANERCC8_HUMANBioGRID29531219 details
TCPE_HUMANSUMO4_HUMANHPRD16236267 details