Entity Details

Primary name CLCN3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51790
EntryNameCLCN3_HUMAN
FullNameH(+)/Cl(-) exchange transporter 3
TaxID9606
Evidenceevidence at protein level
Length818
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCLCN3

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005247 voltage-gated chloride channel activity
GO:0005254 chloride channel activity
GO:0005524 ATP binding
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006885 regulation of pH
GO:0006911 phagocytosis, engulfment
GO:0008021 synaptic vesicle
GO:0008344 adult locomotory behavior
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0012506 vesicle membrane
GO:0015297 antiporter activity
GO:0015299 solute:proton antiporter activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030141 secretory granule
GO:0030165 PDZ domain binding
GO:0030285 integral component of synaptic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0032587 ruffle membrane
GO:0035249 synaptic transmission, glutamatergic
GO:0042581 specific granule
GO:0043231 intracellular membrane-bounded organelle
GO:0043679 axon terminus
GO:0045335 phagocytic vesicle
GO:0045494 photoreceptor cell maintenance
GO:0045794 negative regulation of cell volume
GO:0048388 endosomal lumen acidification
GO:0051932 synaptic transmission, GABAergic
GO:0055037 recycling endosome
GO:0072320 volume-sensitive chloride channel activity
GO:0097401 synaptic vesicle lumen acidification
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:1902476 chloride transmembrane transport
GO:1903428 positive regulation of reactive oxygen species biosynthetic process

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Early endosome membrane
Golgi apparatus membrane
Late endosome membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR000644 CBS domainDomainDomain
IPR001807 Chloride channel, voltage gatedFamilyFamily
IPR002245 Chloride channel ClC-3FamilyFamily
IPR014743 Chloride channel, coreFamilyHomologous superfamily

Diseases

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Interactions

7 interactions