Entity Details

Primary name NR0B1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51843
EntryNameNR0B1_HUMAN
FullNameNuclear receptor subfamily 0 group B member 1
TaxID9606
Evidenceevidence at protein level
Length470
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesNR0B1

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0003714 transcription corepressor activity
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007283 spermatogenesis
GO:0008104 protein localization
GO:0008134 transcription factor binding
GO:0008406 gonad development
GO:0008584 male gonad development
GO:0010894 negative regulation of steroid biosynthetic process
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0019904 protein domain specific binding
GO:0021854 hypothalamus development
GO:0021983 pituitary gland development
GO:0030238 male sex determination
GO:0030325 adrenal gland development
GO:0032448 DNA hairpin binding
GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway
GO:0033327 Leydig cell differentiation
GO:0034451 centriolar satellite
GO:0035902 response to immobilization stress
GO:0042788 polysomal ribosome
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050682 AF-2 domain binding
GO:0060008 Sertoli cell differentiation

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR025900 Nuclear receptor repeatRepeatRepeat
IPR033544 Nuclear receptor subfamily 0 group B member 1/2FamilyFamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01234 DexamethasoneDrugbanksmall molecule
DB14649 Dexamethasone acetateDrugbanksmall molecule