Entity Details

Primary name NCBP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52298
EntryNameNCBP2_HUMAN
FullNameNuclear cap-binding protein subunit 2
TaxID9606
Evidenceevidence at protein level
Length156
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesNCBP2

GO terms

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GOName
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000339 RNA cap binding
GO:0000340 RNA 7-methylguanosine cap binding
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005845 mRNA cap binding complex
GO:0005846 nuclear cap binding complex
GO:0006366 transcription by RNA polymerase II
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0006405 RNA export from nucleus
GO:0006406 mRNA export from nucleus
GO:0006408 snRNA export from nucleus
GO:0006446 regulation of translational initiation
GO:0008334 histone mRNA metabolic process
GO:0008380 RNA splicing
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0016070 RNA metabolic process
GO:0017069 snRNA binding
GO:0031047 gene silencing by RNA
GO:0031124 mRNA 3'-end processing
GO:0031442 positive regulation of mRNA 3'-end processing
GO:0034518 RNA cap binding complex
GO:0042795 snRNA transcription by RNA polymerase II
GO:0045292 mRNA cis splicing, via spliceosome
GO:0046833 positive regulation of RNA export from nucleus
GO:0051168 nuclear export
GO:0098789 pre-mRNA cleavage required for polyadenylation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR027157 Nuclear cap-binding protein subunit 2FamilyFamily
IPR034148 NCBP2, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

30 interactions

InteractorPartnerSourcesPublicationsLink
NCBP2_HUMANNCBP1_HUMANBioGRID, DIP, HPRD, IntAct, MINT11545740 12374755 12434151 17190602 19668212 22365833 22939629 23665581 24981860 26264872 26344197 26382858 26496610 29101316 29395067 29997244 31448526 31467278 32814053 32960270 7478990 9933612 details
NCBP2_HUMANLZTS2_HUMANBioGRID, IntAct25416956 details
NCBP2_HUMANIMB1_HUMANDIP, IntAct19668212 32960270 details
NCBP2_HUMANHNRPF_HUMANBioGRID, HPRD, IntAct32960270 9111328 details
NCBP2_HUMANHNRH1_HUMANBioGRID, HPRD, IntAct32960270 9111328 details
NCBP2_HUMANDX39B_HUMANBioGRID, IntAct17190602 32960270 details
NCBP2_HUMANIKKE_HUMANIntAct17353931 details
NCBP2_HUMANSF3A2_HUMANBioGRID, MINT17332742 details
NCBP2_HUMANPHAX_HUMANBioGRID, IntAct, MINT24981860 26382858 26496610 29395067 32960270 details
NCBP2_HUMANIMA4_HUMANBioGRID, IntAct26382858 26496610 29395067 32960270 details
NCBP2_HUMANPRP4B_HUMANBioGRID, IntAct26496610 29395067 details
NCBP2_HUMANZCH18_HUMANBioGRID, IntAct26382858 29298432 29395067 32960270 details
NCBP2_HUMANNCBP3_HUMANBioGRID, IntAct26382858 29395067 32960270 details
NCBP2_HUMANNELFA_HUMANBioGRID, IntAct26382858 29395067 details
NCBP2_HUMANSRRT_HUMANBioGRID, IntAct, MINT24981860 26382858 29395067 32960270 details
NCBP2_HUMANSRSF6_HUMANBioGRID, IntAct29395067 32960270 details
NCBP2_HUMANICE2_HUMANBioGRID29395067 details
NCBP2_HUMANPDIP3_HUMANBioGRID29395067 details
NCBP2_HUMANRPB1_HUMANBioGRID29395067 details
NCBP2_HUMANPTBP3_HUMANBioGRID29395067 details
NCBP2_HUMANRBBP6_HUMANBioGRID29395067 details
NCBP2_HUMANBRE1A_HUMANBioGRID29395067 details
NCBP2_HUMANBRE1B_HUMANBioGRID29395067 details
NCBP2_HUMANMINT_HUMANBioGRID29395067 details
NCBP2_HUMANZC3H1_HUMANBioGRID29395067 details
NCBP2_HUMANCAPAM_HUMANBioGRID29395067 details
NCBP2_HUMANRPB2_HUMANBioGRID29395067 details
NCBP2_HUMANWAC_HUMANBioGRID29395067 details
NCBP2_HUMANAQR_HUMANBioGRID29395067 details
NCBP2_HUMANIF5_HUMANHPRD11331597 details