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Entity Details
Primary name
PGTB2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P53611
EntryName
PGTB2_HUMAN
FullName
Geranylgeranyl transferase type-2 subunit beta
TaxID
9606
Evidence
evidence at protein level
Length
331
SequenceStatus
complete
DateCreated
1996-10-01
DateModified
2021-06-02
Ontological Relatives
Genes
RABGGTB
GO terms
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GO
Name
GO:0004663
Rab geranylgeranyltransferase activity
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0005968
Rab-protein geranylgeranyltransferase complex
GO:0006464
cellular protein modification process
GO:0007601
visual perception
GO:0008270
zinc ion binding
GO:0018342
protein prenylation
GO:0018344
protein geranylgeranylation
GO:0031267
small GTPase binding
GO:0042981
regulation of apoptotic process
GO:0043687
post-translational protein modification
Subcellular Location
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Domains
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Domain
Name
Category
Type
IPR001330
PFTB repeat
Repeat
Repeat
IPR008930
Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
Family
Homologous superfamily
IPR026873
Geranylgeranyl transferase type-2 subunit beta
Family
Family
Diseases
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Drugs
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Drug
Name
Source
Type
DB04464
N-Formylmethionine
Drugbank
small molecule
DB07780
Farnesyl diphosphate
Drugbank
small molecule
DB07841
Geranylgeranyl diphosphate
Drugbank
small molecule
Interactions
22 interactions
Interactor
Partner
Sources
Publications
Link
PGTB2_HUMAN
ARAF_HUMAN
BioGRID, HPRD, IntAct
12620389
details
PGTB2_HUMAN
SHLB1_HUMAN
BioGRID, IntAct
23414517
details
PGTB2_HUMAN
WDR4_HUMAN
BioGRID, IntAct
25416956
32296183
details
PGTB2_HUMAN
TAFA1_HUMAN
BioGRID, IntAct
25416956
details
PGTB2_HUMAN
TMM25_HUMAN
BioGRID, IntAct
25416956
details
PGTB2_HUMAN
RAB37_HUMAN
BioGRID, IntAct
25416956
details
PGTB2_HUMAN
B4GT7_HUMAN
BioGRID, IntAct
25416956
32296183
details
PGTB2_HUMAN
IBP6_HUMAN
BioGRID, IntAct
32296183
details
PGTB2_HUMAN
PGTA_HUMAN
BioGRID, IntAct
26186194
26344197
28514442
32296183
details
PGTB2_HUMAN
TP4A2_HUMAN
BioGRID, IntAct
11447212
26186194
28514442
details
PGTB2_HUMAN
NPSR1_HUMAN
BioGRID, MINT
28298427
details
PGTB2_HUMAN
RAB3A_HUMAN
BioGRID, HPRD
12535645
7991565
8706741
details
PGTB2_HUMAN
PGTB2_HUMAN
HPRD
11447212
details
PGTB2_HUMAN
RAB5A_HUMAN
BioGRID, HPRD, IntAct
28514442
29568061
7991565
details
PGTB2_HUMAN
FBXL2_HUMAN
BioGRID
24035498
details
PGTB2_HUMAN
RAB1A_HUMAN
HPRD
7991565
details
PGTB2_HUMAN
RAE2_HUMAN
HPRD
12535645
details
PGTB2_HUMAN
RAB6A_HUMAN
HPRD
8175798
details
PGTB2_HUMAN
RB11A_HUMAN
HPRD
9719562
details
PGTB2_HUMAN
RB27A_HUMAN
HPRD
12802062
details
PGTB2_HUMAN
RAB7A_HUMAN
HPRD
11591706
details
PGTB2_HUMAN
HEM0_HUMAN
HPRD
546546
details
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