Entity Details

Primary name LIMK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP53671
EntryNameLIMK2_HUMAN
FullNameLIM domain kinase 2
TaxID9606
Evidenceevidence at protein level
Length638
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesLIMK2

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005801 cis-Golgi network
GO:0005813 centrosome
GO:0006468 protein phosphorylation
GO:0007283 spermatogenesis
GO:0016310 phosphorylation
GO:0030036 actin cytoskeleton organization
GO:0030953 astral microtubule organization
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0051650 establishment of vesicle localization
GO:0060322 head development
GO:0061303 cornea development in camera-type eye
GO:0072686 mitotic spindle
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900182 positive regulation of protein localization to nucleus
GO:1902018 negative regulation of cilium assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR001781 Zinc finger, LIM-typeDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule