Entity Details

Primary name AP2S1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP53680
EntryNameAP2S1_HUMAN
FullNameAP-2 complex subunit sigma
TaxID9606
Evidenceevidence at protein level
Length142
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesAP2S1

GO terms

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GOName
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030100 regulation of endocytosis
GO:0030122 AP-2 adaptor complex
GO:0030666 endocytic vesicle membrane
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0032802 low-density lipoprotein particle receptor catabolic process
GO:0034383 low-density lipoprotein particle clearance
GO:0035615 clathrin adaptor activity
GO:0036020 endolysosome membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0045334 clathrin-coated endocytic vesicle
GO:0048013 ephrin receptor signaling pathway
GO:0048268 clathrin coat assembly
GO:0050690 regulation of defense response to virus by virus
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061024 membrane organization
GO:0072583 clathrin-dependent endocytosis

Subcellular Location

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Subcellular Location
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR000804 Clathrin adaptor complex, small chainSiteConserved site
IPR011012 Longin-like domain superfamilyFamilyHomologous superfamily
IPR016635 Adaptor protein complex, sigma subunitFamilyFamily
IPR022775 AP complex, mu/sigma subunitDomainDomain
IPR027156 AP-2 complex subunit sigmaFamilyFamily

Diseases

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