Entity Details

Primary name SYYC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP54577
EntryNameSYYC_HUMAN
FullNameTyrosine--tRNA ligase, cytoplasmic
TaxID9606
Evidenceevidence at protein level
Length528
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesYARS1

GO terms

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GOName
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0004831 tyrosine-tRNA ligase activity
GO:0005153 interleukin-8 receptor binding
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation
GO:0006915 apoptotic process
GO:0016604 nuclear body

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002305 Aminoacyl-tRNA synthetase, class IcFamilyFamily
IPR002307 Tyrosine-tRNA ligaseFamilyFamily
IPR002547 tRNA-binding domainDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR014729 Rossmann-like alpha/beta/alpha sandwich foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00135 TyrosineDrugbanksmall molecule
DB01766 Beta-(2-Naphthyl)-AlanineDrugbanksmall molecule
DB02709 ResveratrolDrugbanksmall molecule
DB03978 TyrosinalDrugbanksmall molecule
DB07205 N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATEDrugbanksmall molecule
DB08371 p-Benzoyl-L-phenylalanineDrugbanksmall molecule
DB08617 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINEDrugbanksmall molecule