Entity Details

Primary name AIF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55008
EntryNameAIF1_HUMAN
FullNameAllograft inflammatory factor 1
TaxID9606
Evidenceevidence at protein level
Length147
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesAIF1

GO terms

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GOName
GO:0001726 ruffle
GO:0001774 microglial cell activation
GO:0001891 phagocytic cup
GO:0005509 calcium ion binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005884 actin filament
GO:0006911 phagocytosis, engulfment
GO:0006954 inflammatory response
GO:0008284 positive regulation of cell population proliferation
GO:0010468 regulation of gene expression
GO:0016601 Rac protein signal transduction
GO:0030027 lamellipodium
GO:0030041 actin filament polymerization
GO:0030046 parallel actin filament bundle assembly
GO:0030335 positive regulation of cell migration
GO:0032587 ruffle membrane
GO:0032722 positive regulation of chemokine production
GO:0032755 positive regulation of interleukin-6 production
GO:0034599 cellular response to oxidative stress
GO:0042102 positive regulation of T cell proliferation
GO:0048471 perinuclear region of cytoplasm
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0050921 positive regulation of chemotaxis
GO:0051015 actin filament binding
GO:0051017 actin filament bundle assembly
GO:0051764 actin crosslink formation
GO:0071346 cellular response to interferon-gamma
GO:0071672 negative regulation of smooth muscle cell chemotaxis
GO:0071673 positive regulation of smooth muscle cell chemotaxis
GO:0071677 positive regulation of mononuclear cell migration
GO:0090026 positive regulation of monocyte chemotaxis
GO:0090271 positive regulation of fibroblast growth factor production
GO:0097178 ruffle assembly
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:2000406 positive regulation of T cell migration

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR042433 Allograft inflammatory factor 1FamilyFamily

Diseases

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