Entity Details

Primary name ADK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55263
EntryNameADK_HUMAN
FullNameAdenosine kinase
TaxID9606
Evidenceevidence at protein level
Length362
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesADK

GO terms

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GOName
GO:0003723 RNA binding
GO:0004001 adenosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006166 purine ribonucleoside salvage
GO:0006175 dATP biosynthetic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0043101 purine-containing compound salvage
GO:0044209 AMP salvage
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001805 Adenosine kinaseFamilyFamily
IPR002173 Carbohydrate/purine kinase, PfkB, conserved siteSiteConserved site
IPR011611 Carbohydrate kinase PfkBDomainDomain
IPR029056 Ribokinase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00131 Adenosine phosphateDrugbanksmall molecule
DB00171 ATPDrugbanksmall molecule
DB00640 AdenosineDrugbanksmall molecule
DB00811 RibavirinDrugbanksmall molecule
DB01048 AbacavirDrugbanksmall molecule
DB07173 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINEDrugbanksmall molecule
DB07280 5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINEDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ADK_HUMANFICD_HUMANBioGRID, IntAct21988832 details
ADK_HUMANPORED_HUMANBioGRID, IntAct21988832 details