Entity Details

Primary name DLX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56177
EntryNameDLX1_HUMAN
FullNameHomeobox protein DLX-1
TaxID9606
Evidenceevidence at protein level
Length255
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesDLX1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009954 proximal/distal pattern formation
GO:0021544 subpallium development
GO:0021766 hippocampus development
GO:0021879 forebrain neuron differentiation
GO:0021893 cerebral cortex GABAergic interneuron fate commitment
GO:0030154 cell differentiation
GO:0030514 negative regulation of BMP signaling pathway
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043524 negative regulation of neuron apoptotic process
GO:0045597 positive regulation of cell differentiation
GO:0045746 negative regulation of Notch signaling pathway
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046533 negative regulation of photoreceptor cell differentiation
GO:0048706 embryonic skeletal system development
GO:0048715 negative regulation of oligodendrocyte differentiation
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071773 cellular response to BMP stimulus
GO:1902871 positive regulation of amacrine cell differentiation
GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000047 Helix-turn-helix motifSiteConserved site
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DLX1_HUMANSMAD4_HUMANBioGRID, HPRD14671321 details