Entity Details

Primary name WNT3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56703
EntryNameWNT3_HUMAN
FullNameProto-oncogene Wnt-3
TaxID9606
Evidenceevidence at protein level
Length355
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesWNT3

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0001707 mesoderm formation
GO:0005109 frizzled binding
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005796 Golgi lumen
GO:0005886 plasma membrane
GO:0007276 gamete generation
GO:0007411 axon guidance
GO:0009948 anterior/posterior axis specification
GO:0009950 dorsal/ventral axis specification
GO:0010628 positive regulation of gene expression
GO:0016055 Wnt signaling pathway
GO:0019904 protein domain specific binding
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030182 neuron differentiation
GO:0030666 endocytic vesicle membrane
GO:0031012 extracellular matrix
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation
GO:0045165 cell fate commitment
GO:0048018 receptor ligand activity
GO:0048697 positive regulation of collateral sprouting in absence of injury
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0050767 regulation of neurogenesis
GO:0060064 Spemann organizer formation at the anterior end of the primitive streak
GO:0060070 canonical Wnt signaling pathway
GO:0060174 limb bud formation
GO:0060323 head morphogenesis
GO:0061180 mammary gland epithelium development
GO:0070062 extracellular exosome
GO:0071300 cellular response to retinoic acid
GO:0072089 stem cell proliferation
GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
GO:1905474 canonical Wnt signaling pathway involved in stem cell proliferation
GO:1990909 Wnt signalosome

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR005817 WntFamilyFamily
IPR009141 Wnt-3 proteinFamilyFamily
IPR018161 Wnt protein, conserved siteSiteConserved site
IPR043158 Wnt, C-terminal domainFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
WNT3_HUMANAFAM_HUMANUniProt26902720 details
WNT3_HUMANFZD7_HUMANbhf-ucl, Molecular Connections18313787 21314951 details
WNT3_HUMANFZD1_HUMANHPRD10557084 details