Entity Details

Primary name TMPS3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP57727
EntryNameTMPS3_HUMAN
FullNameTransmembrane protease serine 3
TaxID9606
Evidenceevidence at protein level
Length454
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesTMPRSS3

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006508 proteolysis
GO:0006883 cellular sodium ion homeostasis
GO:0007605 sensory perception of sound
GO:0016021 integral component of membrane
GO:0017080 sodium channel regulator activity
GO:0043025 neuronal cell body

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001190 SRCR domainDomainDomain
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR017448 SRCR-like domainDomainDomain
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily
IPR036772 SRCR-like domain superfamilyFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
TMPS3_HUMANEF1A1_HUMANBioGRID, HPRD, IntAct16169070 details
TMPS3_HUMANRXRA_HUMANBioGRID, HPRD, IntAct16169070 details
TMPS3_HUMANTMED7_HUMANBioGRID, IntAct21988832 details