Entity Details

Primary name GSTO1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78417
EntryNameGSTO1_HUMAN
FullNameGlutathione S-transferase omega-1
TaxID9606
Evidenceevidence at protein level
Length241
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesGSTO1

GO terms

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GOName
GO:0004364 glutathione transferase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006749 glutathione metabolic process
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0016491 oxidoreductase activity
GO:0019852 L-ascorbic acid metabolic process
GO:0032259 methylation
GO:0035722 interleukin-12-mediated signaling pathway
GO:0042178 xenobiotic catabolic process
GO:0045174 glutathione dehydrogenase (ascorbate) activity
GO:0050610 methylarsonate reductase activity
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0070062 extracellular exosome
GO:0071243 cellular response to arsenic-containing substance
GO:1901687 glutathione derivative biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004045 Glutathione S-transferase, N-terminalDomainDomain
IPR004046 Glutathione S-transferase, C-terminalDomainDomain
IPR005442 Glutathione S-transferase, omega-classFamilyFamily
IPR010987 Glutathione S-transferase, C-terminal-likeDomainDomain
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily
IPR036282 Glutathione S-transferase, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule
DB00163 Vitamin EDrugbanksmall molecule
DB14001 alpha-Tocopherol succinateDrugbanksmall molecule
DB14002 D-alpha-Tocopherol acetateDrugbanksmall molecule

Interactions

9 interactions