Entity Details

Primary name DEN2B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78524
EntryNameDEN2B_HUMAN
FullNameDENN domain-containing protein 2B
TaxID9606
Evidenceevidence at protein level
Length1137
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesDENND2B

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0055037 recycling endosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Recycling endosome

Domains

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DomainNameCategoryType
IPR001194 cDENN domainDomainDomain
IPR005112 dDENN domainDomainDomain
IPR005113 uDENN domainDomainDomain
IPR037516 Tripartite DENN domainDomainDomain
IPR043153 DENN domain, C-terminal lobeFamilyHomologous superfamily

Diseases

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Interactions

6 interactions